In the human body, creatine is synthesized from amino acids in the liver through a chemical process; it is then transported via the bloodstream to muscle cells, where it is converted into phosphocreatine. Muscle movement relies on energy derived from the breakdown of adenosine triphosphate (ATP). Creatine can regulate water uptake in muscles, causing the muscle cross-section to expand and thereby increasing explosive power.

Extensive in vivo and in vitro studies have confirmed that creatine offers various benefits to the human body:

1. Increases creatine levels in skeletal muscle and boosts energy reserves

2. Modulates glucose metabolism pathways and reduces lactic acid production

3. Increases intramuscular glycogen stores

4. Enhances antioxidant capacity