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- The importance of Autofluorescence Imaging in Clinical Practice
- Fundus Autofluorescence (FAF) imaging is a non-invasive technique which provides information on retinal
- metabolism and health, through showing changes in the integrity of the Retinal Pigment Epithelial (RPE) layer.
- FAF imaging may help to understand metabolic alterations of the RPE in the pathogenesis of several retinal
- disorders.
- Autofluorescence Modality
- Eidon AF with Autofluorescence capability is now an extraordinary tool for obtaining multiple types of highvalue
- information from multiple imaging modalities:
- • White illumination is able to provide high-quality TrueColor imaging
- • Red-free is useful to enhance the detail of the retinal vasculature and retinal nerve fiber layer
- • Infrared light provides information corresponding to the choroid
- • Autofluorescence allows the assessment of the Retinal Pigment Epithelial (RPE) layer
- Autofluorescence Key Principles
- FAF provides clinically useful information by
- taking an image based on the distribution
- pattern of fluorescent pigments accumulating
- in the RPE, such as lipofuscin:
- • RPE dysfunction: lipofuscin accumulation
- increases FAF signal (bright areas)
- • RPE or photoreceptor death: lipofuscin
- absence decreases FAF signal (dark areas)
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