This assay is intended for the rapid screening and quantification of human insulin in cell culture media.
Insulin is a peptide hormone responsible for regulating the metabolism of glucose and most amino acids in the human body. Insulin plays important roles in human metabolism by controlling cellular intake of glucose, increasing DNA replication, and regulating enzyme activities. Diabetes mellitus develops when the body does not produce enough (Type I) or properly respond to (Type II) insulin. Insulin is measured to monitor the level of endogenous insulin produced by the beta cells, to check for insulin resistance, and to help determine other diseases. Insulin concentration is also measured in insulin injection solutions to ensure the quality of those supplies.
Product Applications:
Monitor human Insulin production in cell cultures
Detect insulin in extract of islets of Langerhans cells
Verify insulin concentration in injection solutions.
The FRET-PINCER® assay is ideally suited for the rapid, simultaneous measurement of human insulin levels in large numbers of test samples due to its speed and simplicity. It is readily adaptable to the high-throughput screening platforms currently being used in drug discovery research.
More information at: http://mediomics.com/product/human-insulin-fret-pincer-assay-kit-384-well-format/