Studies have shown that sperm DNA fragmentation may result from the aberrant assembly of chromosome and excessive production of reactive oxygen species (ROS) or pathological apoptosis. Fertilization by fragmented -DNA sperm may cause sterility, habitual abortion and lower pregnancy rate in Assisted Reproductive Technology (ART) treatment.
It was reported that the rate of abortion caused by sperm DNA fragmentation was higher than other factors in the process of IVF or ICSI treatment.
The testing principle of SpermFunc® DNAf is based on SCD technology (Sperm Chromatin Dispersion Test), which evaluates the levels of sperm DNA fragmentation by the size of the halo and (or) the presence or not. SpermFunc® DNAf can be helpful in the pathogenesis analysis in infertility and natural abortion and the inactive development of embryo. It is of important clinical significance in the selection of ART method and the forecast of pregnancy outcome to test sperm DNA fragmentation by SpermFunc® DNAf .
Features:
1. Using the optimizational method, the results of testing are more specific,
and have the distinct configuration of sperm tail, easy to identify.
2. Various appliances outfitted in the kit, easy to operate.
3.Quick operating within one hour, the result is observed under the ordinary
microscope without any other special instrument, easy to apply in clinic.
4. 40 tests per kit. The economical price but more efficient than the
competitive products in the market..
5.The Pre-coated slides with thicker gel coat are good for sperm
chromatin dispersion, improving the sensitivity.
6.Made by the special advanced technics, the reagents are stable and
reliable with two years period of validity.
7. The unique preservable technology for specimen makes it possible
that the specimen stored for at least 15 days, which can reproduce
results as the fresh one. It is worth to testing in batch in clinic.