Benfotiamine (CAS No. 22457-89-2) has the molecular formula C19H23N4O6PS and a molecular weight of 466.45. It is also known as S-benzoylthiamine O-monophosphate. Regarding its solubility, it is slightly soluble in water and methanol, practically insoluble in ethanol, and insoluble in diethyl ether and chloroform. It dissolves in sodium hydroxide and sodium carbonate solutions, and is slightly soluble in dilute hydrochloric acid. Its melting point is approximately 165°C. Benfotiamine is an organic compound—also referred to as S-benzoylthiamine O-monophosphate—that serves as a lipid-soluble derivative of vitamin B1. Once in the body, it is converted into active vitamin B1. Its bioavailability is 3.6 times that of water-soluble vitamin B1, reaching up to 5 times higher in muscle tissue and up to 25 times higher in the brain.

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