Mangosteen extract refers to active ingredients extracted from mangosteen, a plant belonging to the genus Garcinia of the Clusiaceae family. It contains xanthones, phenolic acids, anthocyanins, condensed tannins and other constituents. It exhibits favorable antioxidant, antibacterial, anti-inflammatory and anti-allergic activities, and has attracted growing attention from specialists in the field of dermatology overseas. At present, cosmetic enterprises from multiple countries including Japan, South Korea, the United States and France have launched cosmetic series with mangosteen extract as the key ingredient, such as products of Japan’s Ishizawa Institute, South Korean brand It’s Skin, and Xango from the United States. It is believed that with the deepening of research on its applications in beauty and skin care, as well as expanding studies on immunity enhancement and anti-proliferation effects, mangosteen extract will enjoy increasingly extensive applications in dermatology.