In mammals, β-nicotinamide mononucleotide (NMN) is produced from nicotinamide (Nam) under the catalysis of NAMPT (a protease in the body). Subsequently, NMN is converted to NAD+ under the catalysis of nicotinamide mononucleotide chemicalbook adenylate transferase. Nicotinamide mononucleotide is a direct way to replenish NAD+. It is precisely by significantly enhancing the repair capacity of intracellular DNA damage that nicotinamide mononucleotide ultimately achieves the effect of reversing aging.

Nicotinamide mononucleotide (β-NM, NMN) is one of the key precursors of NAD+ and a product of the NAMPT reaction, converted to NAD+ by nicotinamide mononucleotide adenylate transferase.